P2X7/P2RX7 Antibody (CL11508)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21196

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # CL11508

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all P2X7/P2RX7 Antibodies »

Product Summary for P2X7/P2RX7 Antibody (CL11508)

Immunogen

This antibody was developed against a Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence of Q99572. Actual immunogen sequence is proprietary.

Reactivity Notes

Rat (85%).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Scientific Data Images for P2X7/P2RX7 Antibody (CL11508)

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Western Blot: P2X7/P2RX7 Antibody [NBP3-21196] -

Analysis in human cell line SK-MEL-30.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebral cortex shows moderate positivity in neuronal processes in neuropil.
Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Immunohistochemistry-Paraffin: P2X7/P2RX7 Antibody [NBP3-21196] -

Staining of human Cerebellum shows strong positivity in neuronal processes in neuropil.
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Applications for P2X7/P2RX7 Antibody (CL11508)

Application
Recommended Usage

Immunohistochemistry

1:500- 1:1000

Immunohistochemistry-Paraffin

1:500- 1:1000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X7/P2RX7

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Long Name

P2X Purinergic Receptor 7

Alternate Names

P2RX7

Gene Symbol

P2RX7

Additional P2X7/P2RX7 Products

Product Documents for P2X7/P2RX7 Antibody (CL11508)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for P2X7/P2RX7 Antibody (CL11508)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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