P2X7/P2RX7 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41300

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all P2X7/P2RX7 Antibodies »

Product Summary for P2X7/P2RX7 Antibody - BSA Free

Immunogen

Antibody was raised against a 17 amino acid peptide near the carboxy terminus of human P2RX7. The immunogen is located within the last 50 amino acids of P2RX7. Amino Acid Squence: RWRIRKEFPKSEGQYS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat: (81%)

Specificity

Multiple isoforms of P2RX7 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

54 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for P2X7/P2RX7 Antibody - BSA Free

Western Blot: P2X7/P2RX7 AntibodyBSA Free [NBP2-41300]

Western Blot: P2X7/P2RX7 AntibodyBSA Free [NBP2-41300]

Western Blot: P2X7/P2RX7 Antibody [NBP2-41300] - Western blot analysis of P2RX7 in 3T3 cell lysate with P2RX7 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody - BSA Free [NBP2-41300]

Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody - BSA Free [NBP2-41300]

Immunocytochemistry/Immunofluorescence: P2X7/P2RX7 Antibody [NBP2-41300] - 3T3 cells with P2RX7 antibody at 5 ug/mL.
Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody - BSA Free [NBP2-41300]

Immunocytochemistry/ Immunofluorescence: P2X7/P2RX7 Antibody - BSA Free [NBP2-41300]

Immunocytochemistry/Immunofluorescence: P2X7/P2RX7 Antibody [NBP2-41300] - Immunofluorescence of P2RX7 in 3T3 cells with P2RX7 antibody at 20 ug/mL.

Applications for P2X7/P2RX7 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20 ug/mL

Western Blot

1-2ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: P2X7/P2RX7

FUNCTION: Receptor for ATP that acts as a ligand gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.; Subcellular location: Membrane; Multi-pass membrane protein.

Long Name

P2X Purinergic Receptor 7

Alternate Names

P2RX7

Gene Symbol

P2RX7

Additional P2X7/P2RX7 Products

Product Documents for P2X7/P2RX7 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for P2X7/P2RX7 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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