p53 DINP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76638

Novus Biologicals, part of Bio-Techne

Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all p53 DINP1 Antibodies »

Product Specifications

Immunogen

Antibody was raised with a synthetic peptide corresponding to 14 amino acids near the amino terminus of human p53DINP1. The immunogen is located within the first 50 amino acids of p53DINP1. Amino Acid Squence: MFQYLNKMFVGEVS

Reactivity Notes

Mouse reactivity per customer review.

Specificity

At least two isoforms of p53DINP1 are known to exist; this antibody will detect both isoforms.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

30 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p53 DINP1 Antibody - BSA Free

Western Blot: p53 DINP1 AntibodyBSA Free [NBP1-76638]

Western Blot: p53 DINP1 AntibodyBSA Free [NBP1-76638]

Western Blot: p53 DINP1 Antibody - BSA Free [NBP1-76638] - p53 DINP1 Antibody [NBP1-76638] - Western blotting showing TP53INP1 protein levels in NIH-H460 cells treated LNA-663. TUBULIN was used as protein loading control. Image collected and cropped by CiteAb from the following publication (nature.com/articles/s41419-017-0080-x) licensed under a CC-BY license.
Immunohistochemistry-Paraffin: p53 DINP1 Antibody - BSA Free [NBP1-76638]

Immunohistochemistry-Paraffin: p53 DINP1 Antibody - BSA Free [NBP1-76638]

Immunohistochemistry-Paraffin: p53 DINP1 Antibody - BSA Free [NBP1-76638] - p53 DINP1 Antibody [NBP1-76638] - Mouse liver using p53DINP1 antibody at 2 ug/ml.
Western Blot: p53 DINP1 AntibodyBSA Free [NBP1-76638]

Western Blot: p53 DINP1 AntibodyBSA Free [NBP1-76638]

Western Blot: p53 DINP1 Antibody - BSA Free [NBP1-76638] - p53 DINP1 Antibody [NBP1-76638] - Expression in human lung tissue lysate with p53DINP1 antibody at (A) 0.5 and (B) 1 u/mL.
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Applications for p53 DINP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

2 ug/ml

Immunohistochemistry-Paraffin

2 ug/ml

Western Blot

0.5-1 ug/ml

Reviewed Applications

Read 1 review rated 4 using NBP1-76638 in the following applications:

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p53 DINP1

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.

Alternate Names

DKFZp434M1317, FLJ22139, p53DINP1, P53DINP1p53-dependent damage-inducible nuclear protein 1, p53-inducible p53DINP1, SIPStress-induced protein, Teap, TP53DINP1, TP53INP1A, TP53INP1B, tumor protein p53 inducible nuclear protein 1, tumor protein p53-inducible nuclear protein 1

Gene Symbol

TP53INP1

UniProt

Q96A56 (Human)

Additional p53 DINP1 Products

Product Documents for p53 DINP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for p53 DINP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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