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p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19549

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-19549-100ul
NBP3-19549-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S01-4A5

Concentration

0.3 mg/ml

Product Summary for p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

Immunogen

A synthetic phosphopeptide corresponding to residues surrounding Ser371 of human p70 S6 Kinase beta/S6K2 (Uniprot # Q9UBS0)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

Western Blot: p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5) [NBP3-19549] - Western blot detection of Phospho-p70 S6 Kinase beta/S6RK (Ser371) in K562, Rat Brain, C6, 3T3 cell lysates using NBP3-19549 (1:1000 diluted). Predicted band size: 54kDa. Observed band size: 60kDa.

Applications for p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p70 S6 Kinase beta

S6K2 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Alternate Names

KLS, p70-beta, RPS6KB2, STK14B

Gene Symbol

RPS6KB2

Additional p70 S6 Kinase beta Products

Product Documents for p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p70 S6 Kinase beta/S6K2 [p Ser371] Antibody (S01-4A5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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