PAC1R Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS946

Novus Biologicals, part of Bio-Techne
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NLS946
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Key Product Details

Species Reactivity

Validated:

Human, Monkey

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PAC1R Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human PAC1R.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Marmoset (100%), Gorilla (94%), Bovine (88%), Canine (88%), Equine (82%).

Specificity

Human ADCYAP1R1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PAC1R Antibody - BSA Free

Immunohistochemistry-Paraffin: PAC1R Antibody - BSA Free [NLS946]

Immunohistochemistry-Paraffin: PAC1R Antibody - BSA Free [NLS946]

Immunohistochemistry-Paraffin: PAC1R Antibody [NLS946] - Analysis of anti-ADCYAP1R1 antibody with human brain, pituitary.

Applications for PAC1R Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

7 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PAC1R

The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known. PACAP receptor type 1 expression has been documented in adipose, adrenal, bone, brain, colon, ganglion, heart, lung, ovary, pancreas, placenta, spleen, and uterus. ESTs have been isolated from brain and nerve libraries.

Long Name

Pituitary Adenylate Cyclase Activating Polypeptide 1 Receptor Type I

Alternate Names

ADCYAP1R1, PACAPR, PACAPRI

Entrez Gene IDs

117 (Human)

Gene Symbol

ADCYAP1R1

Additional PAC1R Products

Product Documents for PAC1R Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PAC1R Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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