PADI2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-37918

Novus Biologicals, part of Bio-Techne
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NBP2-37918
NBP2-37918-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (95%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PADI2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PWLPKEDCRDEKVYSKEDLKDMSQMILRTKGPDRLPAGYEIVLYISMSDSDKVGVFYVENPFFGQRYIHILGRRKLYHVVKYTGGS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PADI2 Antibody

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918] - Staining of human cerebral cortex shows strong cytoplasmic positivity in glial cells.
Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918] - Staining of human hippocampus shows strong staining in a subset of glial cells.
Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918]

Immunohistochemistry-Paraffin: PADI2 Antibody [NBP2-37918] - Staining of human colon shows high expression.
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Applications for PADI2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PADI2

PADI2 / PAD2 is a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. Each family member has a distinct substrate specificity and tissue expression pattern. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative disorders, including Alzheimers disease and multiple sclerosis, and it has also been implicated in the pathogenesis of glaucoma.

Long Name

Peptidyl Arginine Deiminase type II

Alternate Names

PAD-H19, PAD2, PDI2, Peptidylarginine Deiminase II

Gene Symbol

PADI2

UniProt

Q9Y2J8 (Human)

Additional PADI2 Products

Product Documents for PADI2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PADI2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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