PAK6 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS6942

Novus Biologicals, part of Bio-Techne
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NLS6942
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Key Product Details

Species Reactivity

Validated:

Human, Canine, Equine, Monkey, Primate

Cited:

Human

Predicted:

Goat (94%), Orangutan (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PAK6 Antibodies »

Product Specifications

Immunogen

Synthetic 18 amino acid peptide from Linker domain of human PAK6.

Epitope

Linker domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Hamster (89%), Bovine (89%), Mouse (83%), Bat (83%).

Specificity

Human PAK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PAK6 Antibody - BSA Free

Immunohistochemistry-Paraffin: PAK6 Antibody - BSA Free [NLS6942]

Immunohistochemistry-Paraffin: PAK6 Antibody - BSA Free [NLS6942]

Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Human Lung, Non-Small Cell Carcinoma. formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Immunohistochemistry-Paraffin: PAK6 Antibody - BSA Free [NLS6942]

Immunohistochemistry-Paraffin: PAK6 Antibody - BSA Free [NLS6942]

Immunohistochemistry-Paraffin: PAK6 Antibody [NLS6942] - Analysis of anti-PAK6 antibody with human brain, neurons and glia at 3.5 ug/ml.

Applications for PAK6 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

3.5 ug/ml
Application Notes
Use in Immunohistochemistry reported in scientific literature (PMID: 22956585)..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PAK6

PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac; however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha. PAK6 expression has been documented in normal human brain, breast, prostate and testis. ESTs have been isolated from several tissue libraries, including normal brain and testis and cancerous cervix and smooth muscle. Caution: PAK6 also has been called P21-Activated Kinase 5 (PAK5); however, PAK5 is a distinct gene found on chromosome 20 p12.2.

Long Name

p21/Cdc42/Rac1-activated Kinase 6

Alternate Names

EC 2.7.11, p21 protein (Cdc42/Rac)-activated kinase 6, p21(CDKN1A)-activated kinase 6, p21-activated kinase 6, p21-activated protein kinase 6, PAK-5, PAK5EC 2.7.11.1, PAK-6, serine/threonine-protein kinase PAK 6

Entrez Gene IDs

56924 (Human)

Gene Symbol

PAK6

Additional PAK6 Products

Product Documents for PAK6 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PAK6 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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