Pappalysin-2/PAPP-A2 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76487

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Pappalysin-2/PAPP-A2 Antibodies »

Product Summary for Pappalysin-2/PAPP-A2 Antibody - BSA Free

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3. The immunogen is located within amino acids 450 - 500 of PLAC3. Amino Acid Squence: VPFRDEKYPRLEVLQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pappalysin-2/PAPP-A2 Antibody - BSA Free

Western Blot: Pappalysin-2/PAPP-A2 AntibodyBSA Free [NBP1-76487]

Western Blot: Pappalysin-2/PAPP-A2 AntibodyBSA Free [NBP1-76487]

Western Blot: Pappalysin-2/PAPP-A2 Antibody [NBP1-76487] - HeLa cell lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody - BSA Free [NBP1-76487]

Immunocytochemistry/ Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody - BSA Free [NBP1-76487]

Immunocytochemistry/Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody [NBP1-76487] - HeLa cells.
Immunocytochemistry/ Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody - BSA Free [NBP1-76487]

Immunocytochemistry/ Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody - BSA Free [NBP1-76487]

Immunocytochemistry/Immunofluorescence: Pappalysin-2/PAPP-A2 Antibody [NBP1-76487] - Immunofluorescence of PAPP A2 in HeLa cells with PAPP A2 antibody at 20 ug/mL.

Applications for Pappalysin-2/PAPP-A2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/ml

Western Blot

1 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pappalysin-2/PAPP-A2

PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.

Long Name

Pregnancy-associated Plasma Protein

Alternate Names

PAPP-A2, PAPPA2, Pappalysin2, PAPPE, PLAC3

Gene Symbol

PAPPA2

UniProt

NP_064714 (Human)

Additional Pappalysin-2/PAPP-A2 Products

Product Documents for Pappalysin-2/PAPP-A2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Pappalysin-2/PAPP-A2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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