PAR4 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS1308

Novus Biologicals, part of Bio-Techne
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NLS1308
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Monkey (94%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PAR4 Antibodies »

Product Specifications

Immunogen

Synthetic 16 amino acid peptide from N-terminal extracellular domain of human PAR4.

Epitope

N-Terminus extracellular domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (94%), Mouse (88%), Porcine (88%), Bovine (81%).

Localization

Integral Memebrane Protein.

Specificity

Human PAR4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PAR4 Antibody - BSA Free

Immunohistochemistry-Paraffin: PAR4 Antibody - BSA Free [NLS1308]

Immunohistochemistry-Paraffin: PAR4 Antibody - BSA Free [NLS1308]

Immunohistochemistry-Paraffin: PAR4 Antibody [NLS1308] - Analysis of anti-F2RL3 / PAR4 antibody with human lung, respiratory epithelium.

Applications for PAR4 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

6 - 13 ug/ml
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PAR4

Proteinase-Activated Receptor 4 (PAR4) is a member of the Proteinase-Activated Receptor subfamily. Along with other protease-activated receptors, PAR4 mediates the effects of the enzyme, thrombin which include activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of the receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR4 expression has been documented in the periphery, primarily in blood platelets.

Long Name

Protease-Activated Receptor 4

Alternate Names

F2RL3, Protease-Activated Receptor 4, Thrombin Receptor-like 3

Entrez Gene IDs

9002 (Human)

Gene Symbol

F2RL3

Additional PAR4 Products

Product Documents for PAR4 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PAR4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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