PARL Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80878

Novus Biologicals, part of Bio-Techne
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NBP1-80878
NBP1-80878-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PARL Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: ESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PARL Antibody

Western Blot: PARL Antibody [NBP1-80878]

Western Blot: PARL Antibody [NBP1-80878]

Western Blot: PARL Antibody [NBP1-80878] - Analysis in human cell line CACO-2 and human cell line HeLa.
Immunocytochemistry/ Immunofluorescence: PARL Antibody [NBP1-80878]

Immunocytochemistry/ Immunofluorescence: PARL Antibody [NBP1-80878]

Immunocytochemistry/Immunofluorescence: PARL Antibody [NBP1-80878] - Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
Immunohistochemistry-Paraffin: PARL Antibody [NBP1-80878]

Immunohistochemistry-Paraffin: PARL Antibody [NBP1-80878]

Immunohistochemistry-Paraffin: PARL Antibody [NBP1-80878] - Staining of human gallbladder shows moderate cytoplasmic positivity in glandular cells.

Applications for PARL Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PARL

PARL encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Long Name

Presenilins Associated Rhomboid-like Protein

Alternate Names

PSARL1, RHBDS1

Entrez Gene IDs

55486 (Human)

Gene Symbol

PARL

UniProt

Q9H300 (Human)

Additional PARL Products

Product Documents for PARL Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PARL Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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