Pax5/BSAP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38790

Novus Biologicals, part of Bio-Techne
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NBP2-38790-25ul
NBP2-38790
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Key Product Details

Species Reactivity

Validated:

Human, Rat, Hamster

Cited:

Rat, Hamster

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

IF/IHC, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Pax5/BSAP Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SGILGITSPSADTNKRKRDEGIQESPVPNGHSLPGRDFLRKQMRGDLFTQQQL

Reactivity Notes

Use in Hamster reported in scientific literature (PMID:34159329). Use in Rat reported in scientific publication (PMID: 32622430).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pax5/BSAP Antibody

Pax5/BSAP Antibody Western Blot: Pax5/BSAP Antibody [NBP2-38790]

Western Blot: Pax5/BSAP Antibody [NBP2-38790]

Analysis in human tonsil tissue.

Applications for Pax5/BSAP Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

Reactivity reported in (PMID:35982658)

Western Blot

0.04-0.4 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP2-38790 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pax5/BSAP

PAX5 encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternatively spliced transcript variants encoding different isoforms have been described but their biological validity has not been determined. [provided by RefSeq]

Long Name

Paired Box Gene 5/B-cell Specific Activator Protein

Alternate Names

BSAP

Gene Symbol

PAX5

UniProt

Q02548

Additional Pax5/BSAP Products

Product Documents for Pax5/BSAP Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Pax5/BSAP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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