PC6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87326

Novus Biologicals, part of Bio-Techne
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NBP1-87326
NBP1-87326-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PC6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YLEHVVVRITITHPRRGDLAIYLTSPSGTRSQLLANRLFDHSMEGFKNWEFMTIHCWGERAAGDWVLEVYDTPSQLRNFKTPGKLKEWSLVLYGTSVQPYSPTNEFPKVERFRYSRVEDPTDD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PC6 Antibody

Immunocytochemistry/ Immunofluorescence: PC6 Antibody [NBP1-87326]

Immunocytochemistry/ Immunofluorescence: PC6 Antibody [NBP1-87326]

Immunocytochemistry/Immunofluorescence: PC6 Antibody [NBP1-87326] - Immunofluorescent staining of human cell line RH-30 shows localization to the Golgi apparatus.
Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326]

Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326]

Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326] - Staining in human duodenum and lymph node tissues using anti-PCSK5 antibody. Corresponding PCSK5 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326]

Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326]

Immunohistochemistry-Paraffin: PC6 Antibody [NBP1-87326] - Staining of human duodenum shows high expression.
View 1 more images

Applications for PC6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PC6

PC6 is encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Two alternatively spliced transcripts are described for this gene but only one has its full length nature known. [provided by RefSeq]

Alternate Names

EC 3.4.21, EC 3.4.21.-, EC 3.4.21.61, EC 3.4.21.75, FLJ11149, FLJ16215, hPC6, PC5PC6A, PC6prohormone convertase 5, Proprotein convertase 5, Proprotein convertase 6, proprotein convertase PC5, proprotein convertase subtilisin/kexin type 5, protease PC6, SPC6, Subtilisin/kexin-like protease PC5

Gene Symbol

PCSK5

Additional PC6 Products

Product Documents for PC6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PC6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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