PCBD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57448

Novus Biologicals, part of Bio-Techne
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NBP2-57448
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCBD1 Antibodies »

Product Summary for PCBD1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: YNKVHITLSTHECAGLSERDINLASFIEQVAVSMT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PCBD1 Antibody

Western Blot: PCBD1 Antibody [NBP2-57448]

Western Blot: PCBD1 Antibody [NBP2-57448]

Western Blot: PCBD1 Antibody [NBP2-57448] - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma and human liver tissue.
Immunocytochemistry/ Immunofluorescence: PCBD1 Antibody [NBP2-57448]

Immunocytochemistry/ Immunofluorescence: PCBD1 Antibody [NBP2-57448]

Immunocytochemistry/Immunofluorescence: PCBD1 Antibody [NBP2-57448] - Staining of human cell line Hep G2 shows localization to nucleoplasm.

Applications for PCBD1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCBD1

The PCBD1 gene encodes pterin-4 alpha-carbinolamine dehydratase, an enzyme involved in phenylalanine hydroxylation. Adeficiency of this enzyme leads to hyperphenylalaninemia. The enzyme regulates the homodimerization of thetranscription factor hepatocyte nucle

Alternate Names

4-alpha-hydroxy-tetrahydropterin dehydratase, DCoH, DCOHpterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1), Dimerization cofactor of hepatocyte nuclear factor 1-alpha, Dimerization cofactor of HNF1, PCBDdimerizing cofactor for HNF1,6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocytenuclear factor 1 alpha (TCF1), PCDEC 4.2.1.96, Phenylalanine hydroxylase-stimulating protein, PHS, Pterin carbinolamine dehydratase, pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocytenuclear factor 1 alpha, pterin-4-alpha-carbinolamine dehydratase

Gene Symbol

PCBD1

Additional PCBD1 Products

Product Documents for PCBD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCBD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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