PCDHA6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-69060

Novus Biologicals, part of Bio-Techne
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NBP2-69060
NBP2-69060-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCDHA6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PSLSPCPIMMGKAENQDLNEDHDAKV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PCDHA6 Antibody

Immunohistochemistry: PCDHA6 Antibody [NBP2-69060]

Immunohistochemistry: PCDHA6 Antibody [NBP2-69060]

Immunohistochemistry: PCDHA6 Antibody [NBP2-69060] - Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in cells in molecular layer.

Applications for PCDHA6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCDHA6

PCDHA6 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Alternate Names

CNR2, CNRN2, CNRS2, CRNR2, KIAA0345-like 8, PCDH-ALPHA6, PCDH-alpha-6, protocadherin alpha 6, protocadherin alpha-6

Gene Symbol

PCDHA6

Additional PCDHA6 Products

Product Documents for PCDHA6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCDHA6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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