PCDHB15 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-56997

Novus Biologicals, part of Bio-Techne
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NBP1-56997
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all PCDHB15 Antibodies »

Product Summary for PCDHB15 Antibody

Immunogen

Synthetic peptides corresponding to PCDHB15 (protocadherin beta 15) The peptide sequence was selected from the N terminal of PCDHB15. Peptide sequence VMEETERGSFVANLANDLGLGVGELAERGARVVSEDNEQGLQLDLQTGQL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PCDHB15 Antibody

Western Blot: PCDHB15 Antibody [NBP1-56997]

Western Blot: PCDHB15 Antibody [NBP1-56997]

Western Blot: PCDHB15 Antibody [NBP1-56997] - Hela cell lysate, concentration 0.2-1 ug/ml.

Applications for PCDHB15 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCDHB15

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

Alternate Names

PCDH-BETA15, PCDH-beta-15, protocadherin beta 15, protocadherin beta-15

Gene Symbol

PCDHB15

UniProt

Q9Y5E8 (Human)

Additional PCDHB15 Products

Product Documents for PCDHB15 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCDHB15 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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