PCDHGA2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68635

Novus Biologicals, part of Bio-Techne
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NBP2-68635-25ul
NBP2-68635
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCDHGA2 Antibodies »

Product Summary for PCDHGA2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ADEGYYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PCDHGA2 Antibody

Immunocytochemistry/ Immunofluorescence: PCDHGA2 Antibody [NBP2-68635]

Immunocytochemistry/ Immunofluorescence: PCDHGA2 Antibody [NBP2-68635]

Immunocytochemistry/Immunofluorescence: PCDHGA2 Antibody [NBP2-68635] - Staining of human cell line U-2 OS shows localization to nucleus & plasma membrane.

Applications for PCDHGA2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Recommended conditions: Fixation/Permeabilization: PFA/Triton X-100
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PCDHGA2

PCDHGA2 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Alternate Names

PCDH-gamma-A2, protocadherin gamma subfamily A, 2, protocadherin gamma-A2

Gene Symbol

PCDHGA2

Additional PCDHGA2 Products

Product Documents for PCDHGA2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PCDHGA2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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