PCDHGA5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-43756

Novus Biologicals, part of Bio-Techne
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NBP2-43756
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (98%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCDHGA5 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PCDHGA5. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (98%), Mouse (86%), Rat (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

101 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PCDHGA5 Antibody

Western Blot: PCDHGA5 Antibody [NBP2-43756]

Western Blot: PCDHGA5 Antibody [NBP2-43756]

Western Blot: PCDHGA5 Antibody [NBP2-43756] - Analysis of various whole cell extracts (30 ug) were separated by 7.5% SDS-PAGE, and the membrane was blotted with PCDHGA5 antibody diluted by 1:2000.

Applications for PCDHGA5 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PCDHGA5

PCDHGA5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Alternate Names

cadherin ME3, CDH-GAMMA-A5, ME3, MGC142020, PCDH-GAMMA-A5, protocadherin gamma subfamily A, 5, protocadherin gamma-A5

Gene Symbol

PCDHGA5

Additional PCDHGA5 Products

Product Documents for PCDHGA5 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PCDHGA5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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