PCDHGB4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15065

Novus Biologicals, part of Bio-Techne
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NBP2-15065
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PCDHGB4 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human PCDHGB4. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (100%), Mouse (85%), Bovine (85%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PCDHGB4 Antibody

Western Blot: PCDHGB4 Antibody [NBP2-15065]

Western Blot: PCDHGB4 Antibody [NBP2-15065]

Western Blot: PCDHGB4 Antibody [NBP2-15065] - Sample (30 ug of whole cell lysate) A: HCT116 7. 5% SDS PAGE; antibody diluted at 1:1000.
Immunohistochemistry-Paraffin: PCDHGB4 Antibody [NBP2-15065]

Immunohistochemistry-Paraffin: PCDHGB4 Antibody [NBP2-15065]

Immunohistochemistry-Paraffin: PCDHGB4 Antibody [NBP2-15065] - Paraffin-embedded Colon ca, using antibody at 1:500 dilution.

Applications for PCDHGB4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PCDHGB4

This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. This particular family member is expressed in fibroblasts and is thought to play a role in wound healing in response to injury. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq]

Alternate Names

cadherin 20, Cadherin-20, CDH20cadherin-20, FIB2fibroblast cadherin FIB2, Fibroblast cadherin-2, MGC138293, MGC142167, PCDH-gamma-B4, protocadherin gamma subfamily B, 4, protocadherin gamma-B4

Gene Symbol

PCDHGB4

UniProt

Q9UN71 (Human)

Additional PCDHGB4 Products

Product Documents for PCDHGB4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PCDHGB4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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