PDE2A Antibody (4F4)

Novus Biologicals, part of Bio-Techne | Catalog # H00005138-M01

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
H00005138-M01
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4F4

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE2A Antibodies »

Product Specifications

Immunogen

PDE2A (NP_002590, 850 a.a. ~ 940 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. REKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPDLDGTRAPINGCCSLDA

Localization

Cell Membrane

Specificity

PDE2A - phosphodiesterase 2A, cGMP-stimulated

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for PDE2A Antibody (4F4)

Western Blot: PDE2A Antibody (4F4) [H00005138-M01]

Western Blot: PDE2A Antibody (4F4) [H00005138-M01]

Western Blot: PDE2A Antibody (4F4) [H00005138-M01] - PDE2A monoclonal antibody (M01), clone 4F4 Analysis of PDE2A expression in IMR-32.
Sandwich ELISA: PDE2A Antibody (4F4) [H00005138-M01] - Detection limit for recombinant GST tagged PDE2A is approximately 0.03ng/ml as a capture antibody.

Applications for PDE2A Antibody (4F4)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PDE2A

Cyclic nucleotides are important intracellular second messengers which play an important role in a variety of signal transduction process. The cyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodiesterases. One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE2. Two genes, PDE2A and PDE2B, have been identified and cloned and they both have an apparent molecular weight of 100 kDA. PDE2A has specificity for cAMP and its activity is modulated by the presence of cGMP. In contrast, PDE2B does not hydrolyze cGMP nor its activity is altered by the presence of cGMP. Western blot analyses of PDE2A reveals that it is present in a variety of tissues including neocortex, cerebellum, heart, kidney lungs, pulmonary artery and skeletal muscle.

Long Name

cGMP-dependent 3',5'-cyclic phosphodiesterase

Alternate Names

CGS-PDE, cGSPDE, IDDPADS, PDE2A1

Entrez Gene IDs

5138 (Human)

Gene Symbol

PDE2A

OMIM

602658 (Human)

UniProt

NP_002590 (Human)

Additional PDE2A Products

Product Documents for PDE2A Antibody (4F4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PDE2A Antibody (4F4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.