PDE6 beta Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-95225

Novus Biologicals, part of Bio-Techne
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NBP2-95225-0.02ml
NBP2-95225-0.1ml
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDE6 beta Antibodies »

Product Specifications

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NP_001138763.1). MSLSEEQARSFLDQNPDFARQYFGKKLSPENVAAACEDGCPPDCDSLRDLCQVEESTALLELVQDMQESINMERVVFKVLRRLCTLLQADRCSLFMYRQRNGVAELATRLFSVQPDSVLEDCLVPPDSEIVFPLDIGVVGHVAQTKKMVNVEDVAECPHFSSFADELTDYKTKNMLATPIMNGKDVVAVI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDE6 beta Antibody - BSA Free

Western Blot: PDE6 beta AntibodyBSA Free [NBP2-95225]

Western Blot: PDE6 beta AntibodyBSA Free [NBP2-95225]

Western Blot: PDE6 beta Antibody [NBP2-95225] - Analysis of extracts of various cell lines, using PDE6 beta at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit . Exposure time: 90s.
Immunohistochemistry-Paraffin: PDE6 beta Antibody - BSA Free [NBP2-95225]

Immunohistochemistry-Paraffin: PDE6 beta Antibody - BSA Free [NBP2-95225]

Immunohistochemistry-Paraffin: PDE6 beta Antibody [NBP2-95225] - Paraffin-embedded rat retina using PDE6 beta .
Immunohistochemistry-Paraffin: PDE6 beta Antibody - BSA Free [NBP2-95225]

Immunohistochemistry-Paraffin: PDE6 beta Antibody - BSA Free [NBP2-95225]

Immunohistochemistry-Paraffin: PDE6 beta Antibody [NBP2-95225] - Paraffin-embedded mouse retina using PDE6 beta .

Applications for PDE6 beta Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:100

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.3), 50% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PDE6 beta

Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Long Name

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta

Alternate Names

GMP-PDE beta, PDE6B, PDEB

Gene Symbol

PDE6B

Additional PDE6 beta Products

Product Documents for PDE6 beta Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PDE6 beta Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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