PDE6A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB120-5660

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB120-5660
NB120-5660-0.025ml
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Bovine, Sheep

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE6A Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues M(16) P Q F A K E Y F D R K L R(29) C of human PDE6 alpha'.

Localization

Plasma membrane

Specificity

PDE6 alpha’

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDE6A Antibody

Western Blot: PDE6A Antibody [NB120-5660]

Western Blot: PDE6A Antibody [NB120-5660]

Western Blot: PDE6A Antibody [NB120-5660] - Analysis of PDE6 alpha’ on sheep retinal extracts.

Applications for PDE6A Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
WB: Detects an approx. 90 kDa representing PDE6 alpha' from sheep retinal extract.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PDE6A

This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.

Long Name

Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha

Alternate Names

GMP-PDE alpha, PDE V-B1, PDEA

Entrez Gene IDs

281973 (Bovine)

Gene Symbol

PDE6A

Additional PDE6A Products

Product Documents for PDE6A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PDE6A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.