PDE7B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85987

Novus Biologicals, part of Bio-Techne
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NBP1-85987
NBP1-85987-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDE7B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDRHFMLQIALKCADICNPCRIWEMSKQWSERVCEEFYRQGELEQKFELEISPLCNQQKDSIPSIQIGFMSYIVEPLFREWAHFTGNSTLSENMLGHLAHNKAQWKSLLPRQHRSRGSS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDE7B Antibody

Western Blot: PDE7B Antibody [NBP1-85987]

Western Blot: PDE7B Antibody [NBP1-85987]

Western Blot: PDE7B Antibody [NBP1-85987] - Analysis in human cell line U-2197.
Immunocytochemistry/ Immunofluorescence: PDE7B Antibody [NBP1-85987]

Immunocytochemistry/ Immunofluorescence: PDE7B Antibody [NBP1-85987]

Immunocytochemistry/Immunofluorescence: PDE7B Antibody [NBP1-85987] - Staining of human cell line HeLa shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PDE7B Antibody [NBP1-85987]

Immunohistochemistry-Paraffin: PDE7B Antibody [NBP1-85987]

Immunohistochemistry-Paraffin: PDE7B Antibody [NBP1-85987] - Staining of human kidney shows strong cytoplasmic positivity in subsets of tubules.

Applications for PDE7B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PDE7B

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.

Long Name

cAMP-specific 3',5'-cyclic phosphodiesterase 7B

Alternate Names

bA472E5.1, cAMP-specific 3'-5'-cyclic phosphodiesterase 7B, EC 3.1.4, EC 3.1.4.17, high-affinity cAMP-specific 3'-5'-cyclic phosphodiesterase, MGC88256, phosphodiesterase 7B, rolipram-insensitive phosphodiesterase type 7

Gene Symbol

PDE7B

Additional PDE7B Products

Product Documents for PDE7B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDE7B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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