PDZD2/PDZK3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38305

Novus Biologicals, part of Bio-Techne
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NBP2-38305
NBP2-38305-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDZD2 Antibodies »

Product Summary for PDZD2/PDZK3 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: VVPEAKASRGGLPSLANGQGIYSVKPLLDTSRNLPATDEGDIISVQETSCLVTDKIKVTRRHYCYEQNWPHESTSFFSVKQRIKSFENLANADRPVAKSG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDZD2/PDZK3 Antibody

Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP2-38305]

Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP2-38305]

Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP2-38305] - Staining of human testis shows cytoplasmic positivity in cells in seminiferous ducts and Leydig cells.

Applications for PDZD2/PDZK3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PDZD2

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

PDZ Domain Containing 2

Alternate Names

AIPC, KIAA0300, Papin, Pin1

Gene Symbol

PDZD2

UniProt

O15018 (Human)

Additional PDZD2 Products

Product Documents for PDZD2/PDZK3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDZD2/PDZK3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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