PDZD2/PDZK3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-17289

Novus Biologicals, part of Bio-Techne
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NBP3-17289-100ul
NBP3-17289-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PDZD2 Antibodies »

Product Summary for PDZD2/PDZK3 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SKVARHFHSPPIILSSPNMVNGLEHDLLDDETLNQYETSINAAASLSSFSVDVPKNGESVLENLHISESQDLDDLLQKP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PDZD2/PDZK3 Antibody

Immunocytochemistry/ Immunofluorescence: PDZD2/PDZK3 Antibody [NBP3-17289]

Immunocytochemistry/ Immunofluorescence: PDZD2/PDZK3 Antibody [NBP3-17289]

Immunocytochemistry/Immunofluorescence: PDZD2/PDZK3 Antibody [NBP3-17289] - Staining of human cell line EFO-21 shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP3-17289]

Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP3-17289]

Immunohistochemistry-Paraffin: PDZD2/PDZK3 Antibody [NBP3-17289] - Staining of human testis shows strong cytoplasmic positivity in cells in seminiferous ducts.

Applications for PDZD2/PDZK3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence, PFA/Triton X-100 is recommended for fixation/permeabilization.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PDZD2

Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis. Two transcript variants encoding different isoforms have been found for this gene.

Long Name

PDZ Domain Containing 2

Alternate Names

AIPC, KIAA0300, Papin, Pin1

Gene Symbol

PDZD2

Additional PDZD2 Products

Product Documents for PDZD2/PDZK3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDZD2/PDZK3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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