PEG10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13749

Novus Biologicals, part of Bio-Techne
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NBP2-13749
NBP2-13749-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PEG10 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: QCIHIERRLARAAAARKPRSPPRALVLPHIASHHQVDPTEPVGGARMRLTQEEKERRRKLNLCLYCGTGGHYADNCPAKASKSS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PEG10 Antibody

Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749]

Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749]

Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749] - Analysis in human placenta and prostate tissues using Anti-PEG10 antibody. Corresponding PEG10 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: PEG10 Antibody [NBP2-13749]

Immunocytochemistry/ Immunofluorescence: PEG10 Antibody [NBP2-13749]

Immunocytochemistry/Immunofluorescence: PEG10 Antibody [NBP2-13749] - Staining of human cell line Hep G2 shows localization to nucleus & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749]

Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749]

Immunohistochemistry-Paraffin: PEG10 Antibody [NBP2-13749] - Staining of human prostate shows low expression as expected.
View 1 more images

Applications for PEG10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For ICC/IF /Permeabilization: PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PEG10

paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frame shifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

Long Name

Paternally Expressed 10

Alternate Names

EDR, HB-1, Mar2, MEF3 Like 1, MEF3L, MEF3L1, RGAG3, RTL2, SIRH1

Gene Symbol

PEG10

Additional PEG10 Products

Product Documents for PEG10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PEG10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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