Periostin is a disulfide linked 90 kDa 811 amno acid protein originally isolated as a osteoblastspecific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1(TGFbeta1) and bone morphogenetic protein (BMP)-2. OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart.

Long Name

Osteoblast Specific Factor 2

Alternate Names

Fasciclin I-like, OSF-2, OSF2, POSTN, TRIF52

Gene Symbol

POSTN

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Product Documents for Periostin/OSF-2 Antibody (POSTN/8165R) [HRP]

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Product Specific Notices for Periostin/OSF-2 Antibody (POSTN/8165R) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Periostin/OSF-2 Antibody (POSTN/8165R) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24006H

Key Product Details

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Product Specifications

Immunogen

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Applications for Periostin/OSF-2 Antibody (POSTN/8165R) [HRP]

Immunohistochemistry-Paraffin

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Stability & Storage

Background: Periostin/OSF-2