Periplakin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19775

Novus Biologicals, part of Bio-Techne
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NBP2-19775
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (91%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Periplakin Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the N-terminus region of human Periplakin. The exact sequence is proprietary.

Localization

Cell junction; desmosome; Cytoplasm; cytoskeleton; Cell membrane (By similarity); Nucleus (By similarity); Mitochondrion (By similarity)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

205 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Periplakin Antibody

Western Blot: Periplakin Antibody [NBP2-19775]

Western Blot: Periplakin Antibody [NBP2-19775]

Western Blot: Periplakin Antibody [NBP2-19775] - Sample (30 ug of whole cell lysate) A: U87-MG 5% SDS PAGE gel, diluted at 1:5000.
Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775]

Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775]

Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775] - Paraffin-embedded mouse prostate. Periplakin antibody [N1N2], N-term dilution: 1:500.
Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775]

Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775]

Immunohistochemistry-Paraffin: Periplakin Antibody [NBP2-19775] - Paraffin-embedded U87 xenograft. Periplakin antibody [N1N2], N-term dilution: 1:500.

Applications for Periplakin Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Periplakin

The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq]

Alternate Names

190 kDa paraneoplastic pemphigus antigen, 195 kDa cornified envelope precursor protein, KIAA0568, MGC134872, periplakin

Gene Symbol

PPL

UniProt

O60437 (Human)

Additional Periplakin Products

Product Documents for Periplakin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Periplakin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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