Peroxiredoxin 3 Antibody (S07-3I3)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19906

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19906-100ul
NBP3-19906-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S07-3I3

Concentration

0.3 mg/ml

View all Peroxiredoxin 3 Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Peroxiredoxin 3 (Uniprot # P30048)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Peroxiredoxin 3 Antibody (S07-3I3)

Western Blot: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906]

Western Blot: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906]

Western Blot: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906] - Western blot detection of Peroxiredoxin 3 in Hela, HL-60, using NBP3-19906 (1:1000 diluted)
Immunohistochemistry-Paraffin: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906]

Immunohistochemistry-Paraffin: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906]

Immunohistochemistry-Paraffin: Peroxiredoxin 3 Antibody (S07-3I3) [NBP3-19906] - Immunohistochemistry of Peroxiredoxin 3 in paraffin-embedded Human Cholangiocarcinoma using NBP3-19906 at dilution 1/50

Applications for Peroxiredoxin 3 Antibody (S07-3I3)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/2000-1/10000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Peroxiredoxin 3

The peroxiredoxin (PRX) family comprises six antioxidant proteins, PRX I, II, III, IV, V and VI, which protect cells from reactive oxygen species (ROS) by preventing the metal-catalyzed oxidation of enzymes. The PRX proteins primarily utilize thioredoxin as the electron donor for antioxidation, although they are fairly promiscuous with regard to the hydroperoxide substrate. In addition to protection from ROS, peroxiredoxins are also involved in cell proliferation, differentiation and gene expression. PRX I, II, IV and VI show diffuse cytoplasmic localization, while PRX III and V exhibit distinct mitochondrial localization. The human PRX I gene encodes a protein that is expressed in several tissues, including liver, kidney, testis, lung and nervous system. PRX II is expressed in testis, while PRX III shows expression in lung. PRX I, II and III are overexpressed in breast cancer and may be involved in its development or progression. Upregulated protein levels of PRX I and II in Alzheimer's disease (AD) and Down syndrome (DS) indicate the involvement of PRX I and II in their pathogenesis.

Alternate Names

AOP-1, MER5, PRDX3, SP-22

Gene Symbol

PRDX3

Additional Peroxiredoxin 3 Products

Product Documents for Peroxiredoxin 3 Antibody (S07-3I3)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Peroxiredoxin 3 Antibody (S07-3I3)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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