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PGLYRP3/PGRPIA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-85468

Novus Biologicals, part of Bio-Techne
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NBP2-85468-0.1ml

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Specifications

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PGLYRP3/PGRPIA. Peptide sequence: SVCSQMLRGLQSHSVYTIGWCDVAYNFLVGDDGRVYEGVGWNIQGLHTQG The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for PGLYRP3/PGRPIA Antibody

Western Blot: PGLYRP3/PGRPIA Antibody [NBP2-85468]

Western Blot: PGLYRP3/PGRPIA Antibody [NBP2-85468]

Western Blot: PGLYRP3/PGRPIA Antibody [NBP2-85468] - WB Suggested Anti-PGLYRP3 Antibody. Titration: 1.0 ug/ml. Positive Control: Fetal Heart

Applications for PGLYRP3/PGRPIA Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PGLYRP3/PGRP-I alpha

Primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria (1,2) and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRP-S, PGRP-Ia , and PGRP-I

Long Name

Peptidoglycan Recognition Protein Intermediate, Alpha/Peptidoglycan Recognition Protein 3

Alternate Names

PGRP-I alpha, PGRP1A, PGRPI alpha, PGRPIA

Gene Symbol

PGLYRP3

Additional PGLYRP3/PGRP-I alpha Products

Product Documents for PGLYRP3/PGRPIA Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PGLYRP3/PGRPIA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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