Phospholipase C delta 1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87557

Novus Biologicals, part of Bio-Techne
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NBP1-87557
NBP1-87557-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (90%), Rat (90%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Phospholipase C delta 1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EAFYKMLTQRVEIDRTFAEAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQRQMTKDGFLMYLLSADGSAFSLAHRRVYQDMGQP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Phospholipase C delta 1 Antibody

Immunohistochemistry: Phospholipase C delta 1 Antibody [NBP1-87557]

Immunohistochemistry: Phospholipase C delta 1 Antibody [NBP1-87557]

Immunohistochemistry: Phospholipase C delta 1 Antibody [NBP1-87557] - Staining of human testis shows cytoplasmic positivity in cells in seminiferus ducts.

Applications for Phospholipase C delta 1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Phospholipase C delta 1

Phospholipase C delta 1, also known by its gene name PLCD1, has a 756 amino acid long isoform that is approximately 86 kDa and a 777 amino acid long isoform that is approximately 88 kDa. Phospholipase C delta 1 is a member of the phospholipase C family and plays a critical role in the production of intercellular second messenger molecules. Phospholipase C delta 1 is a tumor suppressor and mutations in PLCD1 may be a cause of hereditary leukonychia. Currently research on Phospholipase C delta 1 is related to several diseases and disorders including nail disorders, squamous cell carcinoma, Huntington's disease, Alzheimer's disease, colon carcinoma, breast cancer, esophagitis and hypertension. Phospholipase C delta 1 has also been shown to interact with CALM1, CALM2, CALM3, TGM2 and KPNB1 in pathways such as IGF1R signaling, PKA signaling, sweet taste signaling and CREB Pathway.

Long Name

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

Alternate Names

Phospholipase C-III, PLC-delta-1, PLC-III, PLCD1

Gene Symbol

PLCD1

Additional Phospholipase C delta 1 Products

Product Documents for Phospholipase C delta 1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Phospholipase C delta 1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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