PHOX2A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-26140

Novus Biologicals, part of Bio-Techne
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NBP2-26140
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PHOX2A Antibodies »

Product Specifications

Immunogen

Peptide with sequence KGEARCSSEDDDSKE corresponding to internal region according to NP_005160.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PHOX2A Antibody

Western Blot: PHOX2A Antibody [NBP2-26140]

Western Blot: PHOX2A Antibody [NBP2-26140]

Western Blot: PHOX2A Antibody [NBP2-26140] - NBP2-26140 (1ug/ml) staining of Human Adrenal Gland lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for PHOX2A Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:32000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 26 kDa band observed in human adrenal gland and uterus lysates (calculated MW of 29.7 kDa band according to NP_005160.2).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PHOX2A

PHOX2A is encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles.

Alternate Names

aristaless (Drosophila) homeobox, aristaless homeobox (Drosophila), fibrosis ofextraocular muscles, congenital, 2, autosomal recessive, aristaless homeobox homolog, Aristaless homeobox protein homolog, arix homeodomain protein, ARIX1 homeodomain protein, ARIXNCAM2, CFEOM2MGC52227, paired mesoderm homeobox protein 2A, paired-like homeobox 2apaired-like (aristaless) homeobox 2a, PMX2AFEOM2

Entrez Gene IDs

401 (Human)

Gene Symbol

PHOX2A

Additional PHOX2A Products

Product Documents for PHOX2A Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PHOX2A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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