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PI 4 Kinase type 2 beta Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-74233

Novus Biologicals, part of Bio-Techne
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NBP1-74233

Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Synthetic peptides corresponding to the N terminal of Pi4k2b. Immunizing peptide sequence EDPEFADIVLKAEQAIEIGVFPERISQGSSGSYFVKDSKRNIIGVFKPKS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PI 4 Kinase type 2 beta Antibody

Western Blot: PI 4 Kinase type 2 beta Antibody [NBP1-74233]

Western Blot: PI 4 Kinase type 2 beta Antibody [NBP1-74233]

Western Blot: PI 4 Kinase type 2 beta Antibody [NBP1-74233] - Titration: 1.0 ug/ml Positive Control: Mouse Liver.

Applications for PI 4 Kinase type 2 beta Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PI 4 Kinase type 2 beta

Together with PI4K2A and the type III PI4Ks (PIK4CA and PIK4CB) Pi4k2b contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol (PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate (PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate (InsP3). Pi4k2b contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

Long Name

Phosphatidylinositol 4-kinase type 2-beta

Alternate Names

EC 2.7.1.67, PI4K2B, PI4KII-BETA

Gene Symbol

PI4K2B

UniProt

Additional PI 4 Kinase type 2 beta Products

Product Documents for PI 4 Kinase type 2 beta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PI 4 Kinase type 2 beta Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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