PICALM Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76254

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all PICALM Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human PICALM. The immunogen is located within the first 50 amino acids of PICALM. Amino Acid Squence: KATTHEIMGPKKKH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PICALM Antibody - BSA Free

Western Blot: PICALM AntibodyBSA Free [NBP1-76254]

Western Blot: PICALM AntibodyBSA Free [NBP1-76254]

Western Blot: PICALM Antibody [NBP1-76254] - EL4 cell lysate with PICALM antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: PICALM Antibody - BSA Free [NBP1-76254]

Immunocytochemistry/ Immunofluorescence: PICALM Antibody - BSA Free [NBP1-76254]

Immunocytochemistry/Immunofluorescence: PICALM Antibody [NBP1-76254] - Immunofluorescence of PICALM in human brain tissue with PICALM antibody at 20 ug/mL.
PICALM Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: PICALM Antibody - BSA Free [NBP1-76254] -

Immunocytochemistry/ Immunofluorescence: PICALM Antibody - BSA Free [NBP1-76254] - Immunofluorescence of PICALM in human brain tissue with PICALM antibody at 20 u/mL.
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Applications for PICALM Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PICALM

PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).

Alternate Names

CALMclathrin assembly lymphoid-myeloid leukemia, Clathrin assembly lymphoid myeloid leukemia protein, CLTHphosphatidylinositol-binding clathrin assembly protein, LAP, phosphatidylinositol binding clathrin assembly protein

Gene Symbol

PICALM

UniProt

NP_009097 (Human)

Additional PICALM Products

Product Documents for PICALM Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PICALM Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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