Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # Lise-1

Format

BSA Free

Concentration

1 mg/ml

View all PIDD Antibodies »

Product Specifications

Immunogen

Mouse PIDD (Death Domain).

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for PIDD Antibody (Lise-1) - BSA Free

Western Blot: PIDD Antibody (Lise-1)BSA Free [NBP3-11673]

Western Blot: PIDD Antibody (Lise-1)BSA Free [NBP3-11673]

Western Blot: MDA5 Antibody (Hely-1) [NBP3-11673] - Mouse PIDD is detected in primary MEF cells using MDA5 antibody (Hely-1). Method:Cell extracts from mouse embryo fibroblasts (MEFs) either from WT (A-B) or PIDD KO cells (C-D) were separated by SDS-PAGE under reducing conditions, transferred to nitrocellulose and incubated with anti-PIDD (mouse), mAb (Lise-1) (1ug/ml). Proteins were visualized by a chemiluminescence detection system.

Applications for PIDD Antibody (Lise-1) - BSA Free

Application
Recommended Usage

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 10% glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIDD

The protein encoded by the LRDD gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. (provided by RefSeq)

Long Name

p53-Induced Protein With A Death Domain

Alternate Names

LRDD

Gene Symbol

PIDD1

Additional PIDD Products

Product Documents for PIDD Antibody (Lise-1) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PIDD Antibody (Lise-1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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