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PIG3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-33237

Novus Biologicals, part of Bio-Techne
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NBP1-33237

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Full length human PIG3 Recombinant protein.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PIG3 Antibody

Western Blot: PIG3 Antibody [NBP1-33237]

Western Blot: PIG3 Antibody [NBP1-33237]

Western Blot: PIG3 Antibody [NBP1-33237] - Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE; antibody diluted at 1:1000.
Immunocytochemistry/ Immunofluorescence: PIG3 Antibody [NBP1-33237]

Immunocytochemistry/ Immunofluorescence: PIG3 Antibody [NBP1-33237]

Immunocytochemistry/Immunofluorescence: PIG3 Antibody [NBP1-33237] - Paraformaldehyde-fixed A549, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: PIG3 Antibody [NBP1-33237]

Immunohistochemistry-Paraffin: PIG3 Antibody [NBP1-33237]

Immunohistochemistry-Paraffin: PIG3 Antibody [NBP1-33237] - Paraffin-embedded H441 xenograft, using antibody at 1:500 dilution.

Applications for PIG3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PIG3

The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Alternate Names

p53-induced gene 3 protein, PIG3quinone oxidoreductase homolog, quinone oxidoreductase PIG3, tumor protein p53 inducible protein 3, Tumor protein p53-inducible protein 3

Gene Symbol

TP53I3

Additional PIG3 Products

Product Documents for PIG3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PIG3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.