PINCH1/LIMS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19354

Novus Biologicals, part of Bio-Techne
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NBP2-19354
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Xenopus (98%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PINCH1 Antibodies »

Product Summary for PINCH1/LIMS1 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human PINCH1/LIMS1. The exact sequence is proprietary.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PINCH1/LIMS1 Antibody

Western Blot: PINCH1/LIMS1 Antibody [NBP2-19354]

Western Blot: PINCH1/LIMS1 Antibody [NBP2-19354]

Western Blot: PINCH1/LIMS1 Antibody [NBP2-19354] - A: Hela.
Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-19354]

Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-19354]

Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-19354] - Analysis of paraffin-embedded BT474 xenograft, using antibody at 1:100 dilution.

Applications for PINCH1/LIMS1 Antibody

Application
Recommended Usage

Immunohistochemistry

10 - 1:500

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PINCH1

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq]

Long Name

Particularly Interesting New Cys-His Protein 1

Alternate Names

LIMS1

Gene Symbol

LIMS1

UniProt

P48059 (Human)

Additional PINCH1 Products

Product Documents for PINCH1/LIMS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PINCH1/LIMS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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