Pinin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87784

Novus Biologicals, part of Bio-Techne
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NBP1-87784
NBP1-87784-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Pinin Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Pinin Antibody

Western Blot: Pinin Antibody [NBP1-87784]

Western Blot: Pinin Antibody [NBP1-87784]

Western Blot: Pinin Antibody [NBP1-87784] - Analysis in human cell line HepG2.
Immunocytochemistry/ Immunofluorescence: Pinin Antibody [NBP1-87784]

Immunocytochemistry/ Immunofluorescence: Pinin Antibody [NBP1-87784]

Immunocytochemistry/Immunofluorescence: Pinin Antibody [NBP1-87784] - Staining of human cell line A-431 shows localization to nuclear speckles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Pinin Antibody [NBP1-87784]

Immunohistochemistry-Paraffin: Pinin Antibody [NBP1-87784]

Immunohistochemistry-Paraffin: Pinin Antibody [NBP1-87784] - Staining of human cerebral cortex shows strong nuclear positivity in neuronal cells.
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Applications for Pinin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Pinin

PNN is a nuclear and cell adhesion-related protein involved in cell adhesion, mRNA processing, and transcriptional regulation. PNN functions as a transcriptional regulator by relieving CtBP1-mediated repression of the E-cadherin gene. In the role of mRNA processing, PNN functions as a splicing regulator. The role of PNN in transcription and mRNA processing suggests the role of PNN as a coupling factor for the two processes.

Alternate Names

140 kDa nuclear and cell adhesion-related phosphoprotein, Desmosome-associated protein, Domain-rich serine protein, DRS protein, DRSP, DRSSR-like protein, Melanoma metastasis clone A protein, memA, neutrophil protein, Nuclear protein SDK3, pinin, pinin, desmosome associated protein, SDK3

Gene Symbol

PNN

Additional Pinin Products

Product Documents for Pinin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Pinin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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