PKHD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89003

Novus Biologicals, part of Bio-Techne
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NBP1-89003
NBP1-89003-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PKHD1 Antibodies »

Product Summary for PKHD1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: KTTTVNYVRDTLSNPRGWMALLLDQETYSLQSENLWINRSLQYSATFDNFAPGNYLLLVHTDLPPYPDILLRCGSRVGLSFPFLPSPGQNQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PKHD1 Antibody

Immunohistochemistry: PKHD1 Antibody [NBP1-89003]

Immunohistochemistry: PKHD1 Antibody [NBP1-89003]

Immunohistochemistry: PKHD1 Antibody [NBP1-89003] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

Applications for PKHD1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PKHD1

Found mainly in the cytoplasm and plasma membrane, PKHD1 plays an important role in protein binding and receptor activity. The protein encoded by PKHD1 has a single transmembrane (TM) spanning domain and various copies of an immunoglobulin-like plexin-transcription-factor domain. More specifically, these transcripts encode products which lack the TM and may be secreted. In humans, PKHD1 is highly expressed in the kidney by acting as a receptor protein in the cortical and medullary collecting ducts. Diseases associated with PKHD1 include polycystic kidney and hepatic disease, liver disease, neoplasia, fibrosis, cancer, adenocarcinoma and prostate cancer.

Alternate Names

polycystic kidney and hepatic disease 1 (autosomal recessive)

Gene Symbol

PKHD1

Additional PKHD1 Products

Product Documents for PKHD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PKHD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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