PLA2R1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-46116

Novus Biologicals, part of Bio-Techne
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NBP1-46116
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Canine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Flow Cytometry, Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PLA2R1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-EKKKDTPKQHGT corresponding to internal region according to NP_031392.3, NP_001007268.1, NP_001182570.1.

Specificity

This antibody is expected to recognize all reported isoforms (NP_031392.3; NP_001007268.1; NP_001182570.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Theoretical MW

153 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PLA2R1 Antibody

Flow Cytometry: PLA2R1 Antibody [NBP1-46116]

Flow Cytometry: PLA2R1 Antibody [NBP1-46116]

Flow Cytometry: PLA2R1 Antibody [NBP1-46116] - Analysis of paraformaldehyde fixed HEK293 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Applications for PLA2R1 Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/ml

Peptide ELISA

1:1000
Application Notes
Use in Western blot reported in scientific literature (PMID: 24500714).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PLA2R1

Secretory phospholipases A2 (PLA2s) have been purified from a variety of mammalian tissues as well as from insect and snake venoms. The prototype group I PLA2, the pancreatic PLA2 (PLA2G1B; MIM 172410), is involved in digestion, smooth muscle contraction, and cell proliferation. The prototype group II PLA2, the inflammatory-type PLA2 (PLA2G2A; MIM 172411), is involved in inflammatory conditions and is upregulated by proinflammatory cytokines like tumor necrosis factor (TNF; MIM 191160) and interleukin-1 (e.g., IL1B; MIM 147720). Differential toxicity of snake venom Pla2 appears to be linked to a variety of high-affinity receptors in different organs (Ancian et al., 1995 (PubMed 7721806)).(supplied by OMIM)

Long Name

Phospholipase A2 Receptor 1, 180kDa

Alternate Names

CLEC13C, PLA2G1R

Entrez Gene IDs

22925 (Human)

Gene Symbol

PLA2R1

UniProt

Q13018 (Human)

Additional PLA2R1 Products

Product Documents for PLA2R1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PLA2R1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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