Plakophilin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-42354

Novus Biologicals, part of Bio-Techne
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NBP3-42354
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Key Product Details

Species Reactivity

Human, Mouse, Guinea Pig

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

View all Plakophilin 2 Antibodies »

Product Specifications

Immunogen

Immunogen sequence: Asp571-Ala849 (Uniprot#: Q99959)

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Plakophilin 2 Antibody

Plakophilin 2 Antibody

Western Blot: Plakophilin 2 Antibody [NBP3-42354] -

Western Blot: Plakophilin 2 Antibody [NBP3-42354] - Sample: Cavia Salivary gland lysate Primary Ab: 5ug/ml NBP3-42354; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Plakophilin 2 Antibody

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] -

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] - DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 10ug/ml NBP3-42354; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
Plakophilin 2 Antibody

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] -

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] - DAB staining on IHC-P; Samples: Human Stomach Tissue; Primary Ab: 10ug/ml NBP3-42354; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Applications for Plakophilin 2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-50ug/mL

Immunohistochemistry

5-50ug/mL

Western Blot

0.5-5ug/mL

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Plakophilin 2

Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.

Alternate Names

ARVD9, MGC177501, plakophilin 2, plakophilin-2

Gene Symbol

PKP2

Additional Plakophilin 2 Products

Product Documents for Plakophilin 2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Plakophilin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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