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PLC-delta 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68706

Novus Biologicals, part of Bio-Techne
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NBP2-68706
NBP2-68706-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EGHQSEGLRRFGGAFAPARCLTIAFKGRRKNLDLAAPTAEEAQRWVRGLTKLRARLDAMSQRERLDHWIHSYLHRADSNQDSKMSFKEIKSLLRMVNVDMNDMYAYLLFK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PLC-delta 3 Antibody

Western Blot: PLC-delta 3 Antibody [NBP2-68706]

Western Blot: PLC-delta 3 Antibody [NBP2-68706]

Western Blot: PLC-delta 3 Antibody [NBP2-68706] - Analysis in human cell line RT-4.
Immunohistochemistry-Paraffin: PLC-delta 3 Antibody [NBP2-68706]

Immunohistochemistry-Paraffin: PLC-delta 3 Antibody [NBP2-68706]

Immunohistochemistry-Paraffin: PLC-delta 3 Antibody [NBP2-68706] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.

Applications for PLC-delta 3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
Recommended conditions for IHC,Retrieval method: HIER pH6

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PLC-delta 3

PLCD3, also referred to as Phospholipase C-delta-3, is 789 amino acids in length and approximately 89kDa. PLCD3 is a member of the Phospholipase C family and functions to hydrolyze PIP2 to produce the second messangers DAG and IP3. Current research on PLCD3 is being conducted in relation to several diseases and disorders including breast cancer, glioblastoma, Huntington's disease and neurological diseases. PLCD3 has also been shown to have interactions with ITPR1, ITPR3, PIK3C3, DGKE and SKIL in pathways such as the CREB pathway, sweet taste signaling and Inositol phosphate metabolism.

Long Name

Phospholipase C delta 3

Alternate Names

PLCD3, PLCdelta 3

Gene Symbol

PLCD3

Additional PLC-delta 3 Products

Product Documents for PLC-delta 3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PLC-delta 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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