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PLEKHG2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-13773

Novus Biologicals, part of Bio-Techne
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NBP2-13773
NBP2-13773-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: PATTPLPEHKSHMVIPAPSTAFCPEQGHCADIHVPTTPALPKEICSDFTVSVTTPVPKQEGHLDSESPTNIPLTKQGGSRDVQGPDPVCSQPIQPLSWHGSSLDPQGPGDTLPPLPCHLPD

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PLEKHG2 Antibody

Immunocytochemistry/ Immunofluorescence: PLEKHG2 Antibody [NBP2-13773]

Immunocytochemistry/ Immunofluorescence: PLEKHG2 Antibody [NBP2-13773]

Immunocytochemistry/Immunofluorescence: PLEKHG2 Antibody [NBP2-13773] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.
Immunohistochemistry-Paraffin: PLEKHG2 Antibody [NBP2-13773]

Immunohistochemistry-Paraffin: PLEKHG2 Antibody [NBP2-13773]

Immunohistochemistry-Paraffin: PLEKHG2 Antibody [NBP2-13773] - Staining of human bone marrow shows strong cytoplasmic positivity in subset of hematopoietic cells.

Applications for PLEKHG2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PLEKHG2

PLEKHG2 may be a transforming oncogene with exchange activity for CDC42 . May be a guanine-nucleotideexchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits betaand gamma of the heterotrimericguanine nucleotide-binding protein (G protein)

Alternate Names

ARHGEF42, CLGFLJ38638, common-site lymphoma/leukemia guanine nucleotide exchange factor, DKFZp667J2325, FLJ00018, FLJ22458, PH domain-containing family G member 2, pleckstrin homology domain containing, family G (with RhoGef domain) member 2, pleckstrin homology domain-containing family G member 2

Gene Symbol

PLEKHG2

Additional PLEKHG2 Products

Product Documents for PLEKHG2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PLEKHG2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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