Plexin C1 Antibody (1A12)

Novus Biologicals, part of Bio-Techne | Catalog # H00010154-M06

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # 1A12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Plexin C1 Antibodies »

Product Specifications

Immunogen

PLXNC1 (NP_005752, 250 a.a. ~ 348 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PYNYTSGAATGWPSMARIAQSTEVLFQGQASLDCGHGHPDGRRLLLSSSLVEALDVWAGVFSAAAGEGQERRSPTTTALCLFRMSEIQARAKRVSWDFK

Specificity

PLXNC1 (1A12)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Scientific Data Images for Plexin C1 Antibody (1A12)

ELISA: Plexin C1 Antibody (1A12) [H00010154-M06]

ELISA: Plexin C1 Antibody (1A12) [H00010154-M06]

ELISA: Plexin C1 Antibody (1A12) [H00010154-M06] - Detection limit for recombinant GST tagged PLXNC1 is approximately 1ng/ml as a capture antibody.

Applications for Plexin C1 Antibody (1A12)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactive against recombinant protein on ELISA. GST alone used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Plexin C1

Plexin C1, also known by its gene name PLXNC1, is approximately 176kDa and 1,568 amino acids in length. Plexin C1 is localized to the cellular membrane as a transmembrane receptor for the Semaphorins family of proteins. Plexin C1 may be implicated in the regulation of melanocyte adhesion and may be a melanoma tumor suppressor. Current research on Plexin C1 is being performed in relation to several diseases and disorders including Parkinson's disease, leukemia, kidney disease, melanoma, smallpox, prostate cancer, malignant glioma, renal cell carcinoma, ovarian cancer, pancreatic cancer, hepatitis, prostatitis, and pancreatitis. Plexin C1 has also been shown to have interactions with SEMA7A in the axon guidance pathway.

Alternate Names

CD232, PLXNC1, VESPR

Entrez Gene IDs

10154 (Human)

Gene Symbol

PLXNC1

OMIM

604259 (Human)

UniProt

NP_005752 (Human)

Additional Plexin C1 Products

Product Documents for Plexin C1 Antibody (1A12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Plexin C1 Antibody (1A12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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