Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Plxdc2 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human Plxdc2. The immunogen is located within the last 50 amino acids of Plxdc2. Amino Acid Squence: RRPSRWPAMKFRRGSGH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Plxdc2 Antibody - BSA Free

Western Blot: Plxdc2 AntibodyBSA Free [NBP1-76859]

Western Blot: Plxdc2 AntibodyBSA Free [NBP1-76859]

Western Blot: Plxdc2 Antibody [NBP1-76859] - Human colon tissue lysate with Plxdc2 antibody at (A) 0.5 (B) 1 ug/ml.
Immunohistochemistry-Paraffin: Plxdc2 Antibody - BSA Free [NBP1-76859]

Immunohistochemistry-Paraffin: Plxdc2 Antibody - BSA Free [NBP1-76859]

Immunohistochemistry-Paraffin: Plxdc2 Antibody [NBP1-76859] - Human brain tissue using Plxdc2 antibody at 2.5 ug/ml.
Plxdc2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Plxdc2 Antibody - BSA Free [NBP1-76859] -

Immunocytochemistry/ Immunofluorescence: Plxdc2 Antibody - BSA Free [NBP1-76859] - Immunofluorescence of Plxdc2 in Human Brain cells with Plxdc2 antibody at 50 ug/mL.

Applications for Plxdc2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

0.5-1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Plxdc2

Plxdc2, also known as Tumor endothelial marker 7-related (TEM7R) encodes a protein with 57% amino acid identity to TEM7, the most abundant tumor endothelial marker. Plxdc2 is strongly expressed in the endothelial cells of the tumor stroma, but not in the endothelial cells of normal colonic tissue. Plxdc2 is also expressed at high levels in vessels of some normal tissues, with highest expression in muscle and lung. Plxdc2 and TEM7 may be important for tumor angiogenesis in humans. Cortactin was identified as a protein capable of binding to the extracellular region of both TEM7 and Plxdc2, and may provide new opportunities for the delivery of therapeutic and imaging agents to the vessels of solid tumors.

Alternate Names

plexin domain containing 2,1200007L24Rik, plexin domain-containing protein 2, TEM7RFLJ14623, Tumor endothelial marker 7-related protein

Gene Symbol

PLXDC2

UniProt

Q6UX71 (Human)

Additional Plxdc2 Products

Product Documents for Plxdc2 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Plxdc2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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