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PMEL17/SILV Antibody (SR1021)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21629

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21629-100ul
NBP3-21629-50ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1021

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human PMEL17/SILV (Uniprot #: P40967)

Specificity

Detects endogenous levels of total PMEL17/SILV

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PMEL17/SILV Antibody (SR1021)

Western Blot: PMEL17/SILV Antibody (SR1021) [NBP3-21629] -

Western Blot: PMEL17/SILV Antibody (SR1021) [NBP3-21629] - Western blot analysis using NBP3-21629 in human melanoma lysate.

Immunohistochemistry: PMEL17/SILV Antibody (SR1021) [NBP3-21629] -

Immunohistochemistry: PMEL17/SILV Antibody (SR1021) [NBP3-21629] - Immunohistochemical analysis of paraffin-embedded human melanoma, using NBP3-21629.

Applications for PMEL17/SILV Antibody (SR1021)

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PMEL

Melanoma gp100 a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.

Long Name

Premelanosome Protein

Alternate Names

Gp100, ME20, ME20-M, ME20M, PMEL17, SILV

Gene Symbol

PMEL

Additional PMEL Products

Product Documents for PMEL17/SILV Antibody (SR1021)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PMEL17/SILV Antibody (SR1021)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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