PMEL17/SILV Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38185

Novus Biologicals, part of Bio-Techne
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PMEL Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PTAESTGMTPEKVPVSEVMGTTLAEMSTPEATGMTPAEVSIVVLSGTTAAQVTTTEWVETTARELPIPEPEGPDASSIMSTESITGSLGPLLDGTATLRLVKRQVPLDCVLYRYGSFSVTLDIVQGIESAEILQAV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PMEL17/SILV Antibody

Immunohistochemistry-Paraffin: PMEL17/SILV Antibody [NBP2-38185]

Immunohistochemistry-Paraffin: PMEL17/SILV Antibody [NBP2-38185]

Immunohistochemistry-Paraffin: PMEL17/SILV Antibody [NBP2-38185] - Staining in human skin and skeletal muscle tissues using anti-PMEL antibody. Corresponding PMEL RNA-seq data are presented for the same tissues.
Western Blot: PMEL17/SILV Antibody [NBP2-38185]

Western Blot: PMEL17/SILV Antibody [NBP2-38185]

Western Blot: PMEL17/SILV Antibody [NBP2-38185] - Analysis in human cell lines SK-MEL-30 and PC-3 using anti-PMEL antibody. Corresponding PMEL RNA-seq data are presented for the same cell lines. Loading control: anti-GAPDH.

Applications for PMEL17/SILV Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PMEL

Melanoma gp100 a melanosomal matrix protein whose expression is closely correlated with cellular melanin content and which is a frequent melanoma tumor antigen recognized by cytotoxic T lymphocytes. It is a likely candidate gene for some cases of human oculocutaneous albinism not associated with known albinism loci.

Long Name

Premelanosome Protein

Alternate Names

Gp100, ME20, ME20-M, ME20M, PMEL17, SILV

Gene Symbol

PMEL

UniProt

P40967 (Human)

Additional PMEL Products

Product Documents for PMEL17/SILV Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PMEL17/SILV Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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