PMS2 Antibody (BLR142H)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14722

Recombinant Monoclonal
Novus Biologicals, part of Bio-Techne
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NBP3-14722
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Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR142H

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PMS2 Antibodies »

Product Specifications

Immunogen

between 550 and 600

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for PMS2 Antibody (BLR142H)

PMS2 Antibody (BLR142H)

Western Blot;PMS2 Antibody (BLR142H)[NBP3-14722]

Western Blot;PMS2 Antibody (BLR142H) Whole cell lysate (25 µg) from U2OS, Hep-G2, K-562, LNCaP, GaMG, HeLa, Jurkat, and A-549 cells prepared using NETN lysis buffer. Antibody: Rabbit anti-PMS2 recombinant monoclonal antibody used at 1:1000. Secondary: HRP-conjugated goat anti-rabbit IgG . Detection: Chemiluminescence with an exposure time of 30 seconds. Lower Panel: Rabbit anti-COPB2 antibody.

Applications for PMS2 Antibody (BLR142H)

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA and

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: PMS2

PMS2 is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Alternate Names

DNA mismatch repair protein PMS2, EC 3.1, H_DJ0042M02.9, HNPCC4postmeiotic segregation increased (S. cerevisiae) 2, mismatch repair endonuclease PMS2, PMS1 protein homolog 2, PMS2 postmeiotic segregation increased 2 (S. cerevisiae), PMSL2PMS2CL

Gene Symbol

PMS2

Additional PMS2 Products

Product Documents for PMS2 Antibody (BLR142H)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PMS2 Antibody (BLR142H)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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