PNMA1 Antibody (4G6)

Novus Biologicals, part of Bio-Techne | Catalog # H00009240-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 4G6

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PNMA1 Antibodies »

Product Specifications

Immunogen

PNMA1 (NP_006020, 62 a.a. ~ 160 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KAALLELTGAVDYAAIPREMPGKGGVWKVLFKPPTSDAEFLERLHLFLAREGWTVQDVARVLGFQNPTPTPGPEMPAEMLNYILDNVIQPLVESIWYKR

Specificity

PNMA1 - paraneoplastic antigen MA1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Scientific Data Images for PNMA1 Antibody (4G6)

Western Blot: PNMA1 Antibody (4G6) [H00009240-M01]

Western Blot: PNMA1 Antibody (4G6) [H00009240-M01]

Western Blot: PNMA1 Antibody (4G6) [H00009240-M01] - PNMA1 monoclonal antibody (M01), clone 4G6 Analysis of PNMA1 expression in IMR-32.
Immunohistochemistry-Paraffin: PNMA1 Antibody (4G6) [H00009240-M01]

Immunohistochemistry-Paraffin: PNMA1 Antibody (4G6) [H00009240-M01]

Immunohistochemistry-Paraffin: PNMA1 Antibody (4G6) [H00009240-M01] - Analysis of monoclonal antibody to PNMA1 on formalin-fixed paraffin-embedded human stomach. Antibody concentration 3 ug/ml.
Western Blot: PNMA1 Antibody (4G6) [H00009240-M01]

Western Blot: PNMA1 Antibody (4G6) [H00009240-M01]

Western Blot: PNMA1 Antibody (4G6) [H00009240-M01] - PNMA1 monoclonal antibody (M01), clone 4G6. Analysis of PNMA1 expression in Raw 264.7.
View 1 more images

Applications for PNMA1 Antibody (4G6)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PNMA1

PNMA1 (Paraneoplastic antigen MA1) is a protein that is highly restricted to the brain and testis. A paraneoplastic phenomenon is a disease or symptom that is the consequence of the presence of cancer in the body, but is not due to the local presence of cancer cells. These phenomena are mediated by humoral factors (by hormones or cytokines) excreted by tumor cells or by an immune response against the tumor. Sometimes the symptoms of paraneoplastic syndromes show even before the diagnosis of a malignancy. Paraneoplastic syndromes can be divided into 4 main categories: mucocutane paraneoplastic syndromes, neurological paraneoplastic syndromes, haematological paraneoplastic syndromes and endocrine metabolic syndromes. Antibodies against PNMA1 are present in sera from patients suffering from paraneoplastic neurological disorders.

Alternate Names

MA1Neuron- and testis-specific protein 1,37 kDa neuronal protein, paraneoplastic antigen MA1, paraneoplastic neuronal antigen MA1

Entrez Gene IDs

9240 (Human)

Gene Symbol

PNMA1

OMIM

604010 (Human)

UniProt

NP_006020 (Human)

Additional PNMA1 Products

Product Documents for PNMA1 Antibody (4G6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PNMA1 Antibody (4G6)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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