PNMA3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52929

Novus Biologicals, part of Bio-Techne
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NBP1-52929
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all PNMA3 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to PNMA3(paraneoplastic antigen MA3) The peptide sequence was selected from the N terminal of PNMA3. Peptide sequence QDIDYALLPREIPGKGGPWEVIVKPRNSDGEFLNRLNRFLEEERRTVSDM. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PNMA3 Antibody

Western Blot: PNMA3 Antibody [NBP1-52929]

Western Blot: PNMA3 Antibody [NBP1-52929]

Western Blot: PNMA3 Antibody [NBP1-52929] - Titration: 0.2-1 ug/ml, Positive Control: 721_B cell lysate.

Applications for PNMA3 Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PNMA3

The specific function of the protein remains unknown.This gene is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.

Alternate Names

MA3MA5, MGC132756, MGC132758, paraneoplastic antigen MA3, paraneoplastic cancer-testis-brain antigen

Gene Symbol

PNMA3

UniProt

Q9UL41 (Human)

Additional PNMA3 Products

Product Documents for PNMA3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PNMA3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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