PNPLA8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-83098

Novus Biologicals, part of Bio-Techne
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NBP1-83098
NBP1-83098-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PNPLA8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DSGWLKQKNIKQAIKSLKKYSDKSAEKSPFPEEKSHIIDKEEDIGKRSLFHYTSSITTKFGDSFYFLSNHINSYFKRKEKMSQQKENE

Reactivity Notes

Reactivity reported in scientific literature (PMID: 22237407)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PNPLA8 Antibody

Western Blot: PNPLA8 Antibody [NBP1-83098]

Western Blot: PNPLA8 Antibody [NBP1-83098]

Western Blot: PNPLA8 Antibody [NBP1-83098] - Analysis in human cell line U-2197.
Immunocytochemistry/ Immunofluorescence: PNPLA8 Antibody [NBP1-83098]

Immunocytochemistry/ Immunofluorescence: PNPLA8 Antibody [NBP1-83098]

Immunocytochemistry/Immunofluorescence: PNPLA8 Antibody [NBP1-83098] - Staining of human cell line U-2 OS shows localization to nucleoplasm, cytosol & the Golgi apparatus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PNPLA8 Antibody [NBP1-83098]

Immunohistochemistry-Paraffin: PNPLA8 Antibody [NBP1-83098]

Immunohistochemistry-Paraffin: PNPLA8 Antibody [NBP1-83098] - Staining of human duodenum shows strong cytoplasmic positivity in glandular cells.

Applications for PNPLA8 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PNPLA8

Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM]

Alternate Names

calcium-independent phospholipase A2-gamma, EC 3.1.1.5, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2 gamma, IPLA22, IPLA2-2, iPLA2-gamma, IPLA2GIPLA2(GAMMA), membrane-associated calcium-independent phospholipase A2 gamma, patatin-like phospholipase domain containing 8, Patatin-like phospholipase domain-containing protein 8, PNPLA-gamma

Gene Symbol

PNPLA8

Additional PNPLA8 Products

Product Documents for PNPLA8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PNPLA8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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